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May 7, 2007

Symptom Severity Of PBS/IC Difficult To Predict Based On Medical History And Demographics

UroToday.com - The association, if any, between medical or demographic characteristics and symptom severity in chronic prostatitis/ chronic pelvic pain syndrome (CP/CPPS) and PBS/IC patients has not been well studied. Clemens and colleagues from Northwestern University reviewed their patient database covering 1999 to 2002 to identify patients diagnosed with CP/CPPS and IC. Questionnaires were mailed to these patients, and nonresponders were followed up 6 months later. The questionnaires asked for information on demographics, medical history, and smoking and alcohol intake. A standardized mental health questionnaire was administered, and females were sent the O'Leary Sant Symptom and Problem Indexes as well as the AUA Symptom Index. Men were sent the NIH chronic prostatitis symptom index.

Self-reported urinary urgency and frequency, depression and lower education level were independent predictors of symptom severity in men with CP/CPPS and women with PBS/IC. Self-reported pelvic pain, fibromyalgia and a previous heart attack predicted symptom severity in men and postmenopausal status predicted symptom severity in women. The authors conclude that although several common medical conditions are associated with urological pelvic pain syndromes in men women, few of them were predictive of symptom severity in this analysis.

By Philip M Hanno, MD, MPH
Reference:
Journal of Urology, 175:963-967, 2006
Link Here.
Clemens JQ, Brown SO, Kozloff L, Calhoun EA

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